Vesselina G Cooke Selected Research

naporafenib

1/2021

LXH254, a Potent and Selective ARAF-Sparing Inhibitor of BRAF and CRAF for the Treatment of MAPK-Driven Tumors.

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Vesselina G Cooke Research Topics

Disease

11	Neoplasms (Cancer) 01/2021 - 09/2008
2	Leukemia 11/2016 - 10/2015
2	Neoplasm Metastasis (Metastasis) 02/2015 - 09/2011
1	Melanoma (Melanoma, Malignant) 01/2018
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 11/2013
1	Prostatic Neoplasms (Prostate Cancer) 09/2013
1	Renal Cell Carcinoma (Grawitz Tumor) 09/2008
1	Male Infertility (Male Sterility) 01/2008
1	Wounds and Injuries (Trauma) 01/2007

Drug/Important Bio-Agent (IBA)

3	Pharmaceutical PreparationsIBA 01/2021 - 05/2015
2	RAF709IBA 01/2018 - 01/2017
2	Phosphotransferases (Kinase)IBA 01/2017 - 01/2016
2	Proteins (Proteins, Gene)FDA Link 10/2015 - 01/2007
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 09/2011 - 09/2008
1	naporafenibIBA 01/2021
1	VemurafenibIBA 01/2018
1	raf KinasesIBA 01/2018
1	PyransIBA 01/2017
1	MorpholinosIBA 01/2017
1	benzamideIBA 01/2017
1	Biomarkers (Surrogate Marker)IBA 11/2016
1	tyrosine receptor (receptor, tyrosine)IBA 01/2016
1	SHP099IBA 01/2016
1	Non-Receptor Type 11 Protein Tyrosine PhosphataseIBA 01/2016
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2016
1	NVP-CGM097IBA 10/2015
1	Biological ProductsIBA 02/2015
1	Angiopoietin-2IBA 02/2015
1	AngiopoietinsIBA 02/2015
1	TankyrasesIBA 06/2014
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 06/2014
1	ChromatinIBA 11/2013
1	4- chloro- 3',6'- dimethyl- 2,2'- iminodibenzoate (TO 115)IBA 11/2013
1	enzalutamideIBA 09/2013
1	Cre recombinaseIBA 09/2011
1	Thymidine KinaseIBA 09/2011
1	TenascinIBA 09/2011
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 09/2011
1	Angiogenesis InhibitorsIBA 09/2008
1	Integrin alphaVbeta3IBA 09/2008
1	Bevacizumab (Avastin)FDA Link 09/2008
1	type IV collagen alpha3 chain (Goodpasture antigen)IBA 09/2008
1	Peptides (Polypeptides)IBA 09/2008
1	Sperm ProteinsIBA 01/2008

Therapy/Procedure

3	Therapeutics 01/2021 - 05/2015
1	Castration 09/2013